Department of Biomedical Engineering and Computational Science BECS

Programme

Monday, September 8

8:30–11:30Hands-on sessions (Locations: BioMag Laboratory, Haartmaninkatu 4, P-floor / Cognitive Brain Research Unit (CBRU, Siltavuorenpenger 1 B, Helsinki)
Dr. Pantelis Lioumis, BioMag Laboratory, Finland / Tommi Makkonen, M.Sc. University of Helsinki, Finland

12:00–13:00Lunch (to be paid by participants)

13:00–13:30Registration (CBRU)

13:30–17:30Hands-off session: Basics of TMS (Lectures, Location: CBRU, Minerva-tori Siltavuorenpenger 5 A, room K226)
13:30–15:00 Prof. Risto Ilmoniemi, Aalto University, Finland
Introduction to TMS and TMS-EEG
Paper: Ilmoniemi and Kicic 2010  /  Slides  /  Slides


15:00–16:00 Prof. Jari Karhu, Nexstim Oy, Finland
Clinical use of TMS


16:00–17:00 Prof. Matti Hämäläinen, Aalto University, Finland
Smoke Implies Fire: EEG Signals and Their Sources
Paper: Baillet et al 2001, Ray Ramirez

17:30–18:30Transportation to Sannäs Manor (Sannaistentie 540, Sannäs, Finland)

18:30–19:00Registration continues (Sannäs Manor)

19:00–20:00Hands-and-mouth session (Dinner)

20:00–23:00Opening of the summer school and handshake session (Presentation of students and speakers, Miniposters and other methods to learn to know each other)


Tuesday, September 9, 2014

7:00–8:00Breakfast

8:00–9:00Coaching sessions

9:00–10:30Brains-on session
Prof. Ulf Ziemann, Tübingen University Hospital, Germany
Pharmaco-TMS-EEG
Paper: Premoli et al 2014  /  Slides

10:30–10:45Coffee break

10:45–12:15Brains-on session
Prof. Jeff Daskalakis, University of Toronto, Canada
TMS-EEG and the Development of Biomarkers for Psychiatric Illness
Papers: Voineskos et al 2010, Farzan et al 2010, Farzan et al 2013, Rajji et al 2013

12:15–13:15Lunch

13:15–14:45Brains-on session
Prof. Hartwig R. Siebner, Copenhagen University Hospital Hvidovre, Denmark
How can MRI contribute to a better understanding of the neurobiological effects of TMS?
Papers: Herz et al 2014, Siebner et al 2009

14:45–15:15Coffee break

15:15–16:45Students' presentations I

  1. Tuomas Mutanen
  2. Yinming Sun
  3. Suzanne Hut
  4. Niko Mäkelä

16:45–17:00Coffee break

17:00–18:00Brainstorming session

18:00–19:00Poster Session I

  1. Aleksei Gorin
  2. Angelina Maric
  3. Bjørn Juel
  4. Dulce Magdaleno-Arroyo
  5. Elias Casula
  6. Elisa Martin-Arevalo
  7. Elyana Saad
  8. Johanna Metsomaa
  9. Nele De Geeter

19:00–19:30Transportation to Porvoo

19:30–23:30Dinner and visit to Porvoo

23:30–24:00Transportation to Sannäs Manor

00:00–7:30Brains-off session


Wednesday, September 10, 2014

7:30–8:30Breakfast

8:30–9:00Coaching sessions

9:00–10:30Brains-on session
Prof. Marcello Massimini, University of Milan, Italy
TMS/EEG and consciousness
Papers: Massimini et al 2009, Rosanova et al 2012, Casali et al 2013

10:30–10:45Coffee break

10:45–12:15Brains-on session
Prof. Vasilios Kimiskidis, Aristotle University of Thessaloniki, Greece
TMS-EEG in Epilepsy: insight into pathophysiological mechanisms and emerging clinical applications
Paper: Kimiskidis et al 2014

12:15–12:25Group photo

12:25–13:15Lunch

13:15–14:45Brains-on session
Prof. Gesa Hartwigsen, Department of Psychology, Christian-Albrechts-University Kiel, Germany
Multifocal TMS and plasticity in language networks - insights from combined TMS and fMRI
Papers: Hartwigsen et al 2010, Hartwigsen et al 2013  /  Slides

14:45–15:15Coffee break

15:15–16:45Brains-on session
Dr. Sara Määttä, University of Eastern Finland, Kuopio, Finland
TMS-EEG and the developing brain
Papers: Bender et al 2005

16:45–17:00Coffee break

17:00–18:00Brainstorming session

18:00–19:00Poster Session II

  1. Alexander Chervyakov
  2. Asta Kybartaite
  3. Bimal Lakhani
  4. Elisa Kallioniemi
  5. Giuseppe Lanza
  6. Julia Király
  7. Matteo Fecchio
  8. Virginia Conde

19:00–20:00Dinner

20:00–24:00Brains-off-duty session (Sauna 20:00-22:00 and Summer School party)

00:00–7:30Brains-off session


Thursday, September 11, 2014

7:30–8:30Breakfast

8:30–9:00Coaching sessions

9:00–10:30Brains-on session
Fabio Ferrarelli, University of Wisconsin-Madison, USA
Investigating schizophrenia with simultaneous TMS/hd-EEG
Papers: Ferrarelli et al 2008, Ferrarelli et al 2012

10:30–10:45Coffee break

10:45–12:15Brains-on session
Prof. Carlo Miniussi, University of Brescia, Italy
TMS-EEG in the exploration of the human connectome  /  Slides

Abstract: Recent developments in neuroscience have emphasised the importance of integrated distributed networks of brain areas for successful cognitive functioning. Neuroimaging studies adopting analyses from the graph field of mathematics have shown that the brain architecture has a modular organisation in which segregated networks supporting specialised processing are linked through a few long-range connections, ensuring processing integration. Although such architecture is structurally stable, it appears to be flexible in its functioning, enabling long-range connections to regulate the information flow and facilitate communication among the relevant modules, depending on the contingent cognitive demands. Importantly, much of the current understanding of the brain architecture relays on measures of structural connectivity, reflecting anatomical connections, and of functional connectivity, reflecting the temporal correlations between cortical activity. These measures cannot fully explain the causal dynamics of connectivity and their relationship with cognition.
Here the aim is to highlight an emerging distinctive approach based on the direct activation of an area by transcranial magnetic stimulation (TMS) and the simultaneous evaluation of the distribution of this activity in cortical networks by electrophysiological recordings (EEG). By presenting TMS-EEG studies on network dynamics at rest and during cognition, and comparing them with fMRI-based functional connectomics, it will be showed how TMS-EEG data support the general principles of brain architecture inferred from graph theory and provide further insights into the properties of the functional connectome. Moreover, types of data that can be obtained through TMS-EEG will highlighted, such as the timing of signal propagation, the excitatory/inhibitory nature of connections and, most importantly, causality of cortical interactions.

12:15–13:15Lunch

13:15–14:45Brains-on session
Dr. Keiichi Kitajo, RIKEN Brain Science Institute, Japan
TMS-induced phase resetting and information flow in large-scale brain networks
Paper: Kawasaki et al 2014

14:45–15:15Coffee break

15:15–16:00Brains-on session
Dr. Simone Sarasso, University of Milan, Italy
Electrophysiology of cortical lesions: insight from TMS-EEG

16:00–16:45Students' presentations II

  1. Estelle Raffin
  2. Lari Koponen

16:45–17:00Coffee break

17:00–18:00Brainstorming session

18:00–19:00Poster Session III

  1. Christoph Zrenner
  2. Juha Gogulski
  3. Katri Silvennoinen
  4. Koos Zevenhoven
  5. Leo Tomasevic
  6. Maria Nazarova
  7. Margo Detombe
  8. Mikko Nyrhinen
  9. Sergei Tugin

19:00–20:00Dinner

20:00–24:00Brains-off-duty session (outdoor activities and other relaxation)

00:00–7:30Brains-off session


Friday, September 12, 2014

7:30–8:30Breakfast

8:30–11:30Presentations (24/7 summaries of lectures, literature browsing)

11:30–11:45Closing of the summer school

12:00–13:00Lunch

13:00–14:00Transportation to Helsinki

15:00–18:00Hands-on sessions (Locations: BioMag Laboratory, Haartmaninkatu 4, P-floor / Cognitive Brain Research Unit (CBRU, Siltavuorenpenger 1 B, Helsinki)
Dr. Pantelis Lioumis, BioMag Laboratory, Finland / Tommi Makkonen, M.Sc. University of Helsinki, Finland

19:30–24:00Dinner in Helsinki City Center (Location: Kappeli/Kappelin Kellari, Eteläesplanadi 1, 00130 Helsinki)


Saturday, September 13, 2014

9:00–11:30Data analysis workshop (Location: IT classroom in Maarintalo (Maari B & Maari E), Aalto University, Otaniemi, Espoo)
Johanna Metsomaa, M.Sc. Aalto University
Dr. Julio C. Hernandez-Pavon, Aalto University

Topics: basic analysis (filtering, averaging), more advanced methods (PCA, SSP, ICA), source localization  /  Slides  /  Slides

11:30–13:00Lunch (to be paid by participants)

13:00–16:00Data analysis workshop continues
Dr. Silvia Casarotto, University of Milan, Italy
Topics: basic analysis (filtering, averaging), more advanced methods (PCA, SSP, ICA), source localization  /  Slides